#24 Junho 26 - Digoxina, FA, LLM-IA, AVC e Outros...

REVISÕES SISTEMÁTICAS de ECAs

• Efficacy and Safety of Digitalis Glycosides in Heart Failure: A Meta-Analysis | JAMA
• Timing of Complete Revascularization in Patients w/ EAMCESST and Multivessel Disease | Circ Cardiovasc Interv
• Single-Shot Regional Anesthesia for Early Rib Fracture-Associated Pain Management | Acad Emerg Med
• Effectiveness and Tolerability of Pharmacologic Prophylaxis for Chronic Migraine | Annals of Internal Medicine
• Endovascular thrombectomy for patients w/ large-core ischaemic stroke presenting up to 24 h - ATLAS | Lancet

ENSAIOS CONTROLADOS E ALEATORIZADOS (ECAs)

• Digoxin in Patients With Symptomatic Rheumatic Heart Disease – Dig-RHD | JAMA
• L​ow-dose digoxin in patients w/ heart failure w/ reduced or mildly reduced ejection fraction-DECISION | NatMed
• Weight Loss in Older Patients With Persistent Atrial Fibrillation - LOSE-AF | JAMA
• Chronic Subdural Hematoma With Adjunctive Embolization of Middle Meningeal Artery – EMMA-Can | JAMA
• Low-Volume Polyethylene Glycol for Bowel Preparation in Hospitalized Adults - INTERPRET | Annals of IntMed
• Twenty-Three–Year Benefits of Sigmoidoscopy Screening for Colorectal Cancer - NORCCAP | AIM
• Effects of LLM -generated, patient-oriented discharge summaries on patient activation | Lancet Digital Health
• Ticagrelor with aspirin with intravenous thrombolysis in patients with ischaemic stroke in China (TAPIS) | Lancet
• Adjunctive Intra-Arterial Alteplase After Successful Thrombectomy for Acute Ischemic Stroke – CHOICE-2 | JAMA
• Intravenous Tenecteplase Prior to Endovascular Treatment for Ischemic Stroke at 4.5 - 24 H – TNK-PLUS | JAMA
• Endovascular Treatment of Medium-Vessel-Occlusion Strokes – ORIENTAL-MeVO | NEJM
• Endovascular treatment for medium or distal vessel occlusion stroke (DISTAL): 12-month outcomes|LancetNeuro
• Phase 3 Trials of Inhaled Treprostinil for Idiopathic Pulmonary Fibrosis – TETON-1+TETON-2 | NEJM
• Intensive LDL Cholesterol Targeting in Atherosclerotic Cardiovascular Disease - Ez-PAVE | NEJM

Outros ECAs/artigos

Ócio do mês

• Ler na praia no geral :) - li "Diário de um pároco de aldeia" e "Vida do Santo Condestável - Dom Nuno Álvares Pereira" e estou a ler "O Pórtico do Mistério ds Segunda Virtude"
• Mundial de futebol 2026! Sim, são muito mais equipas e jogos - por outro lado, mais países envolvidos. É sempre um entusiasmo.